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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Added/Advanced>websourced from the manufacturer are also available:

C. Antibiotic Use

Cialis (tadalafil) is used to manage blood pressure side effects and protect against infections that may cause painful erections or erections that last longer than 4 hours.

  • Other Bacterial Infections: While the manufacturer recommends taking no more than tadalafil with Cialis, other infections such as cholestasis and urinary tract infections often require daily use.
  • Pregnancy and Lactation Outbreaks: There's no clear evidence that Cialis can harm pregnant or breastfeeding individuals.

Disulfiram Interactions:

Shadok Pharma Limited (Swiss pl Reserved for further review) supplier medicine can be affected by various short-term or long-term health effects from this supplement. Symptoms of a single supplement may include headaches, dizziness, lightheadedness, or fainting.

As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours. Daily Tadalafil use is usually associated with lower incidents and severity of side effects compared to as-needed Tadalafil dosing.

Most common Tadalafil side effects

  • Headache
  • Indigestion
  • Back pain
  • Muscle pain
  • Flushing
  • Stuffy nose

Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:

  • An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
  • Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropath (NAION).
  • Sudden hearing decrease or hearing loss. Some may also have ringing in the ears (tinnitus) or dizziness.

For a complete list of possible side effects,.

Possible drug interactions

Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.

On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

For a complete list of possible drug interactions,.

Other important safety information

Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or healthcare provider.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

  • Tadalafil (Cialis) is a [inaVage] medicine for the treatment of erectile dysfunction (also known as impotence).
  • Patients with active liver or kidney problems or a record ofocardial infarction have Tadalafil at higher than expected risk. Hepatic enzymes (obarbit editore) may cause the medication to be eliminated undigestable.
  • Patients with a history of stroke have not been found to have such a high event-to-event ratio.
  • Patients with an active bowel or overgrowth of the eye (glandular) problem have Tadalafil at increased risk.
  • Patients with a history of blood clots or stroke (such as those with a history of deep vein thrombosis or a history of stroke) have tadalafil at increased risk.

Men with high blood pressure, diabetes, or heart failure, can be prescribed tadalafil to treat symptoms like dizziness, lightheadedness, or fainting.

Tadalafil, the active ingredient in the popular brand name Cialis, treats a variety of conditions, including erectile dysfunction (ED) and benign prostatic hyperplasia (BPH).

It also helps improve blood flow to the penis. Tadalafil works by relaxing muscles in the walls of blood vessels. This helps men who have high blood pressure to have a better erection.

This medication is not approved for use in women.

Tadalafil can cause side effects in people who have certain medical conditions, like: heart disease, high or low blood pressure, high cholesterol, or diabetes.

People who take tadalafil should talk to their doctor before taking tadalafil to help them better manage symptoms. Call your doctor at once if you have sudden vision loss, sudden hearing decrease or sudden hearing loss, or unexplained muscle pain or weakness.

Tadalafil can also cause side effects. Common side effects include:

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhea
  • Headache
Call your doctor if your side effects bother you or don’t go away. Taking tadalafil with food can also cause side effects. Tell your doctor right away if you have any unusual or persistent side effects.

Tadalafil can interact with other medications and food products you may be taking. Tell your doctor if you are taking any of the following:

  • Nitrates
  • Alpha-blockers
  • Antibiotics
  • Antifungal medication
  • Cancer drug or food supplements
  • Antihypertensive medications
  • Antihypertensive agents
  • Anti-nausea or anti-vomiting medication
  • Lithium

Taking tadalafil with certain foods or medications may affect how tadalafil works.

  • Medications for depression or anxiety
  • Other medication for erectile dysfunction
  • Other medications for high blood pressure or other conditions
  • Other medications that are prescribed for anxiety, such as:
  • Beta-blockers (like 'Brigid' or 'Tadalafil') or "GLP-1-receptor agonists" like:
  • Probenecid
  • Other medications for BPH or erectile dysfunction

Your doctor may start you with low doses of tadalafil and increase it slowly over time. This can help to increase blood flow. Your doctor may slowly lower your dose to make sure your blood flow gets back up. Your doctor may then slowly increase your dose to make sure blood flow is back up.

Some people who take tadalafil for a long time may experience mild side effects. These may include:

This is not a complete list of side effects. If you have concerns, contact your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tadalafil is available by prescription only. Many people still take Cialis because of its safety. However, some people prefer to continue taking tadalafil or choose a cheaper alternative. Tell your doctor if you are using any of the following:

  • Medications for diabetes
  • Other medications for ED

Before taking tadalafil, shake the bottle well. Carefully measure the dose using a special measuring device that you can find on your pharmacy’s website. If you are using a measuring device, check the label for instructions. Use a measuring cup to measure the dose. You can also measure the dose on the pill.

Tadalafil can make a big difference to your vision.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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Signs of a serious adverse reaction:

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Signaling this interaction may be with sexual activity or a herbal product you use, especially St.

Add this medication to your daily regimen

Let your doctor know if you are using any of the listed regimens before using Cialis.

Notify your doctor